Hello Rob, you have this message reported because there is a mismatch between the cube version and the authoring version. The Wwise version that is running in the game has to match the authoring version when profiling.
Make sure to use 2015.1.x Mac Authoring when following the Wwise-101 course as the course is not yet 2016.1 compatible. You can download 2015.1.9 authoring from here:
https://www.audiokinetic.com/files/?get=2015.1.9_5624/Wwise_Authoring_Mac_v2015.1.9_Build5624.zip
By the way, make sure to restart the Lesson 1 and create a new project otherwise you will get an error when opening with 2015.1 the project you created with Wwise2016 authoring. (" The project or one of the work units has been saved with a more recent version of Wwise, and can't be opened ")
Hope this helps !